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Can video game–style exercise slow Alzheimer’s risk?

Can video game–style exercise slow Alzheimer’s risk?

Can video game–style exercise slow Alzheimer’s risk?

Priyom Bose

September, 10, 2025

Originally Published Here

Summary

A recent randomized controlled trial published in Alzheimer’s Research & Therapy examined whether adding ‘Brain-IT’ exergame training to standard care could enhance cognition in older adults with mild neurocognitive disorder (mNCD). Over 12 weeks, participants receiving Brain-IT showed significant gains in global cognitive performance and verbal recall, unlike controls. MRI data revealed increased gray matter volume in the hippocampus and thalamus, regions linked to memory, and improvements in white matter integrity. These findings suggest that personalized exergame-based interventions can support neuroplasticity and cognitive function in mNCD, though larger, long-term trials are needed to confirm these promising effects.

Reference

Bose, P. (2025, September 10). Can video game–style exercise slow Alzheimer’s risk? News-Medical. https://www.news-medical.net/news/20250910/Can-video-gamee28093style-exercise-slow-Alzheimere28099s-risk.aspx